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As part of the submission process, authors are required to check off their submission's compliance with all of the following items, and submissions may be returned to authors that do not adhere to these guidelines.

  • The submission has not been previously published, nor is it before another journal for consideration (or an explanation has been provided in Comments to the Editor).
  • The text adheres to the stylistic and bibliographic requirements outlined in the Author Guidelines.
  • The submission file is in OpenOffice, Microsoft Word, or RTF document file format.
  • The manuscript will be checked for plagiarism using Turnitin.
  • Where available, URLs for the references have been provided.
  • The text is single-spaced; uses a 12-point font; employs italics, rather than underlining (except with URL addresses); and all illustrations, figures, and tables are placed within the text at the appropriate points, rather than at the end.
  • Submission also implies that all authors have approved the paper for release and are in agreement with its content.
  • Authors retain copyright and grant the journal right of first open-access publication.
  • The information entered in this website will be used exclusively for the stated purposes of this journal and will not be made available for any other purpose or to any other party.

Full Title for this journal, Times New Roman,11 Font Size, Center, Bold

Running head is a short title (60 characters or fewer, including spaces) that appears at the top of every page of your manuscript, Times New Roman, 11 Font Size, Center

-First Middle Author

Department, Institution

City Postal Code, Country

Clear and concise description of the reported work

-Second Middle Author

Department, Institution

City Postal Code, Country

Clear and concise description of the reported work

-Last Middle Author

Department, Institution

City Postal Code, Country

Clear and concise description of the reported work

*Corresponding author:

Full name

Department, Institution

City Postal Code, Country



Keywords: (3-7 keywords)


(The abstract of the manuscript should not exceed 250 words. Abide strictly by this limitation of length. The abstract should comprehensively but succinctly describe the contents of the paper to the reader, and abbreviations and reference citations should be avoided.) Introduction: Briefly state the problem/issue addressed and background, in language accessible to a general scientific audience. Method: Briefly summarize the method used to address the problem. Results: Provide a brief summary of the results and findings. Conclusions: Give brief concluding remarks on your outcomes.


The background section should be written from the standpoint of researchers without specialist knowledge in that area and must clearly state - and, if helpful, illustrate - the background to the research and its aims. The section should end with a very brief statement of what is being reported in the article [1].


This can be divided into subsections if several methods are described [2].

Subsection 1

Method is described [3].

Subsection 2

Method is described [4].


Result and Discussion

The Results and Discussion may be combined into a single section or presented separately. They may also be broken into subsections with short, informative headings.

Figure 1.   Figures are numbered with Roman numerals and even at the beginning of a sentence

Table 1.  Tables are numbered with Roman numerals and even at the beginning of a sentence


This should state clearly the main conclusions of the research and give a clear explanation of their importance and relevance. Summary illustrations may be included.


These should be included at the end of the text and not in footnotes. Personal acknowledgements should precede those of institutions or agencies.


The references should include only articles that are published or in press. The references are each numbered, ordered sequentially as they appear in the text. Citations in the reference list should contain all named authors, regardless of how many there are.

Please use the following style for references:

Article in a Journal:

  1. Pan GJ, Chang ZY, Schöoler HR, Pei DQ (2002) Stem cell pluripotency and transcription factor Oct4. Cell Res. 12:321-329.https://doi.org/10.1016/j.worlddev.2016.06.010.

Chapter in a Book:

  1. Hirsimaki P, Arstuka AU, Trump BF, Marzella L. Autophagocytosis. In: Trump BF, Arstuka AU, eds.(1983) Pathobiology of cell membranes. New York: Plenum Press. 201-236.

A book:

  1. Kryger M, Roth T, Dement W, eds. (1994) The Principles and Practice of Sleep Medicine. 2nd Edition. Philadelphia:WB Saunders.

Online Publication:

  1. Jelinic P, Stehle JC, Shaw P (2006) The testis-specific factor CTCFL cooperates with the protein methyltransferase PRMT7 in H19 imprinting control region methylation. PLoS Biol. 4: e355. DOI: 10.1371/journal.pbio.0040355.

Article within a journal supplement:

  1. Orengo CA, Bray JE, Hubbard T, LoConte L, Sillitoe I (1999) Analysis and assessment of ab initio three-dimensional prediction, secondary structure, and contacts prediction. Proteins, 43(Suppl 3):149-170.

In press article:

  1. Kharitonov SA, Barnes PJ. Clinical aspects of exhaled nitric oxide. Eur Respir J, in press.

Published abstract:

  1. Zvaifler NJ, Burger JA, Marinova-Mutafchieva L, Taylor P, Maini RN (1999) Mesenchymal cells, stromal derived factor-1 and rheumatoid arthritis [abstract]. Arthritis Rheum. 42:s250.

Article within conference proceedings:

  1. Jones X (1996) Zeolites and synthetic mechanisms. In Proceedings of the First National Conference on Porous Sieves: 27-30 June 1996; Baltimore. Edited by Smith Y. Stoneham: Butterworth-Heinemann.16-27.

Whole issue of journal :

  1. Ponder B, Johnston S, Chodosh L (Eds) (1998) Innovative oncology. In Breast Cancer Res. 10:1-72.

Whole conference proceedings :

  1. Smith Y (Ed) (1996) Proceedings of the First National Conference on Porous Sieves: 27-30 June 1996; Baltimore. Stoneham: Butterworth-Heinemann.

Monograph or book in a series:

  1. Hunninghake GW, Gadek JE (1994) The alveolar macrophage. In Cultured Human Cells and Tissues. Edited by Harris TJR. New York: Academic Press.54-56. [Stoner G (Series Editor): Methods and Perspectives in Cell Biology, vol 1.]

PhD thesis:

  1. Kohavi R (1995) Wrappers for performance enhancement and oblivious decision graphs. PhD thesis. Stanford University, Computer Science Department.

Link / URL:

  1. The Mouse Tumor Biology Database [http://tumor.informatics.jax.org/mtbwi/index.do], accessed date.



Abbreviations should be follow SI symbols and those recommended by the IUPAC. Abbreviations should be defined in brackets after their first mention in the text. Standard units of measurements and chemical symbols of elements may be used without definition in the body of the paper.

Preparing illustrations and figures

Figures and images should be labelled sequentially, numbered and cited in the text. Figures should be referred to specifically in the text of the paper but should be embedded within the text. The legends should be included from the main manuscript text file and being a part of the figure file (using Arabic numerals, maximum figure title is 15 words and detailed legend, up to 300 words). The use of three-dimensional histograms is strongly discouraged when the addition of the third dimension gives no extra information. The following file formats can be accepted:

  • PDF (also especially suitable for diagrams)
  • PNG (preferred format for photos or images)
  • Microsoft Word (figures must be a single page)
  • Power Point (figures must be a single page)
  • TIFF
  • JPEG

Preparing tables

These should be should be numbered in sequence using Arabic numerals (i.e. Table 1, 2, 3 etc.). Tables should also have a title that summarizes the whole table, maximum 15 words. Table should be embedded into the text file but in portrait format (note that tables on a landscape page must be reformatted onto a portrait page or submitted as additional files).

Preparing additional files

Supplementary information is peer-reviewed material directly relevant to the conclusion of an article that cannot be included in the printed version owing to space or format constraints. Any additional files will be linked into the final published article in the form supplied by the author, but will not be displayed within the paper. They will be made available in exactly the same form as originally provided.

If additional material is provided, please list the following information in a separate section of the manuscript text, at the end of the document text file:

  • File name
  • File format (including name and a URL of an appropriate viewer if format is unusual)
  • Title of data
  • Description of data